LONGEVITY & CELLULAR RESEARCH

SS-31

A mitochondria-targeted tetrapeptide studied for protecting mitochondrial function and reducing oxidative stress.

SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide studied for protecting mitochondrial function, reducing oxidative stress, and supporting cellular energy. It has a specific cardiolipin-binding mechanism and has been evaluated in clinical trials for mitochondrial conditions.

Mitochondria-TargetedCardiolipin BindingOxidative StressCellular Energy

Why BLP features SS-31

Included because it has a highly specific, well-characterized mitochondrial mechanism and has been evaluated in human clinical trials for mitochondrial conditions. Its real-world use history is still developing, placing it as an emerging longevity-research compound with strong mechanistic backing.

Mechanism

Selectively targets and binds cardiolipin in the inner mitochondrial membrane.

Stabilizes mitochondrial structure and electron-transport-chain supercomplexes.

Enhances ATP production while reducing reactive oxygen species, without affecting healthy mitochondria.

WHAT THE RESEARCH MEASURED

Research findings

Findings describe study outcomes, not expected personal results.

Human research findings

  • Clinical research (as elamipretide) has evaluated mitochondrial function and exercise tolerance.
  • Reported reduction in mitochondrial oxidative-stress markers.
  • Reported enhanced cellular energy and reduced fatigue in models of aging and dysfunction.
  • Mostly well tolerated; rare mild injection-site reactions, fatigue, or headache.

Mechanistic & supporting research

  • Cardiolipin-targeting mechanism very well characterized.
  • Mitochondrial-protection effects documented in preclinical and clinical research.

Regulatory status

SS-31 (elamipretide) is investigational and not FDA-approved. Sold and offered strictly for laboratory and research use.