Reported research findings
- No established human clinical trials define effective dosing, meaningful fat loss, or safety in people to date.
WEIGHT & METABOLIC RESEARCH
5-Amino-1MQ
Studied in cell and animal models for fat metabolism and for preserving NAD+, the coenzyme cells run on.
5-Amino-1MQ blocks an enzyme called NNMT, which cells use to dispose of the raw material for NAD+—the coenzyme that powers cellular energy production. Blocking it is researched as a way to keep more of that raw material in circulation. Evidence to date is preclinical—demonstrated in cell and animal models—showing effects on fat metabolism and NAD+ levels without changing how much the animals ate. Human efficacy and safety data remain limited.
Why BLP features 5-Amino-1MQ
Included as an emerging research compound with a specific, well-defined enzyme target (NNMT) and compelling preclinical data. Human efficacy and safety data remain limited, so it is presented as experimental despite growing research interest.
Mechanism
Inhibits the NNMT enzyme, which otherwise consumes nicotinamide—the building block cells use to make NAD+.
Raises NAD+ inside the cell, modeled as improving the efficiency of the cell's energy-producing machinery and its ability to burn fat.
In fat-cell models, reduces new fat storage and produces smaller fat cells, shifting them toward the more metabolically active 'brown' type.
WHAT THE RESEARCH MEASURED
Research findings
Findings describe study outcomes, not expected personal results.
Preclinical findings
- In obese animal models: significant reductions in body weight, white adipose tissue mass, and adipocyte size.
- Reported improved insulin sensitivity and lower plasma cholesterol, with enhanced fat burning and no appetite change.
- Reported boosted energy production and mitochondrial function in models.
- Reported very mild tolerability signals; injectable form associated with minimal reported side effects in research use.
Regulatory status
5-Amino-1MQ is investigational with primarily preclinical evidence and no established human efficacy or safety trials. Sold and offered strictly for laboratory and research use.